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PMID: 78

Polyphenols contain hydroxyl groups capable of scavenging ROS and chelating redox-active metals resulting in the suppressed ROS (hydroxyl radicals) via Fenton chemistry or other mechanisms (Simunkova et al

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Despite these strategies, mucoadhesive particles predominantly adhere to the superficial mucus layer and, at least in the upper airways where mucus turnover is rapid with proper hydration (~1020 min) 144,145 , they are quickly cleared