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The peptide upregulates matrix metalloproteinase (MMP) production, facilitating basement membrane degradation necessary for cellular movement and a comprehensive review in Frontiers in Endocrinology has detailed how its actin-binding properties regulate cytoskeletal function across multiple tissue repair contexts

The recommended frequency is once every 3 to 4 days, but it may vary depending on the length of the treatment needle: Using 0.25mm needles: Once every 3 to 4 days Using 0.50mm needles: Once every 1 to 2 weeks Using 1.00mm needles: Once every 3 to 4 weeks Warnings and Precautions For professional use only

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DOI: 10.3390/jcm12175653 59

von Schenck, U., Bender-Gtze, C., & Koletzko, B