ghk cu dry skin PSA] Albeit rare Copper peptide "uglies" are real and scary. Case report and looking for advices : r/SkincareAddiction HealthyDerm Copper Peptides GHK-Cu Blue

The brand tells you it's because they want to give you a well-rounded formula

GHK-Cu has a molecular weight of approximately 341 Da as the free tripeptide (before copper coordination), which puts it near but not comfortably below that threshold

GHK-Cu is generally stable but can potentially be deactivated or cause irritation when combined with certain strong acids (like high concentrations of AHAs or BHAs, particularly Ascorbic Acid/Vitamin C in low pH formulations) and some direct acids (like L-Ascorbic Acid)

It also has significant antioxidant effects and has been shown to inhibit carcinogenic receptor expression, which has led to research into its potential anti-tumor effects in breast and colorectal cancer [5, 6]

Endoplasmic reticulum stress promotes prostate cancer cells to release exosome and up-regulate PD-L1 expression via PI3K/Akt signaling pathway in macrophages