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For example, some very high-dose intravenous (IV) treatments or supplements with synthetic fillers can occasionally cause stress to the system

The clinical manifestations of acne are comedonal, papular, nodular, and cystic lesions, which can result in scarring, post-inflammatory hyperpigmentation, or, less commonly, hypopigmentation (172)

Excessive lipid peroxidation alters the property of membrane and further damage the proteins and nucleic acids, which is implicated in various human pathologies

Moreover, hydroxyproline inhibition could attenuate the sorafenib resistance under hypoxia (Tang et al., 2018)

In addition, TET2 deficiency in murine macrophages increases JNK1 activation-mediated NLRP3 inflammasome activation and BRCC3-mediated NLRP3 deubiquitylation (224)