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Solved 5. Metformin (below) is one of the oldest drugs used Metformin ROS Nrf2 connection in the host defense mechanism against oxidative stress, apoptosis, cancers, and ageing ScienceDirect Isolated Pyridoxine Deficiency Presenting as Muscle Spasms in a Patient With Type 2 Diabetes: A Case Report and Literature Review The American Journal of the Medical Sciences Metformin ReadyRx Co administration of metformin and gallic acid modulates JAK STAT signaling pathway and glutathione metabolism in fructose fed streptozotocin diabetic Rats ScienceDirect

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Methylene blue is generally considered safe when used as a dye for diagnostic purposes, but it must be carefully considered as a medication in pediatric patients