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Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo

Jing X-Z, Yang H-J, Taximaimaiti R, Wang X-P

10.1016/j.freeradbiomed.2020.06.028 105 ReddyP

In Japan, for instance, it is recognized as medicine, and cannot be incorporated as a food additive

NTS were purified by layering on 4 C Percoll gradient suspension containing Eagles minimum essential medium, penicillin-streptomycin (10,000 U per ml penicillin/10,000 U per ml streptomycin), and 1 M HEPES in 0.85% NaCl with cercariae suspension and centrifuged at 500 g for 15 min