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While 5-AR is indeed the gatekeeper of DHT, it is also the gatekeeper for a class of vital brain compounds known as neurosteroids

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These results suggest that T4 therapy enhances the responsiveness of somatotroph cells to GRF in patients with primary hypothyroidism

In conclusion, copper metabolism imbalance not only directly affects the functions of immune cells but also influences the aggregation of -synuclein by altering metal homeostasis within neurons, thereby exacerbating neuroinflammation and neurodegenerative lesions (172)

One common theme is that short-term use (a few weeks) of BPC-157 injections has not revealed obvious red-flag side effects in patients no abnormal lab tests, no acute illnesses which aligns with the idea that its acutely safe