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McInerney, G

These changes enhance the activity of the renin-angiotensin system (RAAS), contributing to vasoconstriction, sodium retention, and heightened blood pressure, thereby exacerbating the risk of hypertension [460]

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Because mesenchymal stem cells (MSCs) have been shown to produce many specific anti-inflammatory effects in neural tissue, "these findings have led to increased interest in MSCs as a potential cell source candidate owing to their immunomodulatory effect [and] MSCs have demonstrated the capability to differentiate into astrocyte-like cells that secrete neurotrophic factors and ameliorate the motor deficits in a rodent model of PD." (4a) (4b)