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Redox regulation of cardiac hypertrophy

Upon inhibition of wild-type p53 in these cells, they surprisingly responded with a drastic IGF-1R downregulation and cell death (Girnita et al, 2000)

The hypocretin/orexin neuropeptides are essential for the maintenance of wakefulness and the suppression of REM sleep, and zebrafish possess a functional hcrt-pineal gland circuit, connecting the hcrt and melatonin systems together in sleep consolidation (Appelbaum et al

This is supported by the decreased expression of autosomal genes encoding members of the electron transport chain complexes IV that was more pronounced with increased time on ART in PWH ( Figure 4C )

Strikingly, selective deletion of EAAT2 in spinal cord astrocytes is sufficient to induce motor neuron degeneration and impairs motor learning and coordination in mice [391]