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Curr Top Med Chem 12:9941007 Baluchnejadmojarad T, Roghani M (2013) Coenzyme q10 ameliorates neurodegeneration, mossy fiber sprouting, and oxidative stress in intrahippocampal kainate model of temporal lobe epilepsy in rat

demonstrated a relationship between high chemerin levels and functional disability in RA patients and found a correlation between functional disability and DAS-28

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A key concept for understanding this interface is the model of allostasis (adaptation) and allostatic load (pathophysiology) [6] that we review below examining this model in relation to new insights from the recent work on the link between mitochondrial metabolism and epigenetic function to promote healthy behaviors and cognitive function