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Another antagonist of MC1R, undecylenoyl phenylalanine, also induced significant lightening of pigmented lesions when applied twice daily at 2% in patients with melasma or SL [118, 119]

The peptide is ideal for pairing with heparin because it essentially blocks heparins action until it is needed in the body, said Atip Lawanprasert, doctoral student in biomedical engineering and first author on the paper

This safe, precise treatment reduces dark spots, pigmentation, acne marks, and sun tan , delivering a more even skin tone with no significant downtime

In fact, it's estimated that around 16,000 people die each year from NSAID (non-steroidal anti-inflammatory drug) use, with another 100,000 hospitalized (source)