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J Cell Biochem 120(6):94219429

Nat Rev Dis Primers (2020) 6(1):7

FAO Irrig Drain 24:144

Berberine is a plant-derived compound with centuries of use in traditional wellness practices and a growing body of modern research behind it

When glucose levels rise, GK is released from glucose kinase regulatory protein (GKRP), translocates to the cytoplasm, and becomes catalytically active, thereby facilitating glycolysis and glycogen synthesis