local glutathione reperfusion protects the rat liver against injury after hypothermic preservation Cardiac Ischaemia–Reperfusion Injury: Pathophysiology, Therapeutic

Guo Q, Shi X, Wang X

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Upon stimulation, Nrf2 is released, translocates to the nucleus, and promotes the expression of antioxidant genes, including heme oxygenase 1 ( HMOX1 ), NAD(P)H quinone dehydrogenase 1 ( NQO1 ), superoxide dismutase ( SOD ), and catalase ( CAT ) (Kansanen et al., 2013

Here are the ingredients Full Ingredient List: Aqua/Water/Eau, Panthenol, Cetearyl Alcohol, Glycerin, Octyldodecanol, Dicaprylyl Carbonate, Butyrospermum Parkii (Shea) Butter, Propanediol, Dicaprylyl Ether, Glyceryl Stearate Citrate, Niacinamide, Cetearyl Olivate, Sambucus Nigra Seed Oil, Tocopheryl Acetate, Mangifera Indica (Mango) Seed Butter, Astrocaryum Murumuru Seed Butter, Rubus Chamaemorus Seed Oil, Ribes Nigrum (Black Currant) Seed Oil, Sodium Hyaluronate, Polyglutamic Acid, Ceramide Ng, Ceramide Np, Ceramide Ap, Ceramide Eop, Zinc Pca, Sodium Pca, Magnesium Pca, Manganese Pca, Saccharomyces/Zinc Ferment, Saccharomyces/Copper Ferment, Saccharomyces/Iron Ferment, Saccharomyces/Potassium Ferment, Saccharomyces/Silicon Ferment, Saccharomyces/Manganese Ferment, Tocopherol, Cyanocobalamin, Sodium Lactate, Linoleic Acid, Linolenic Acid, Sodium Lauroyl Lactylate, Phytosphingosine, Cholesterol, Sorbitan Olivate, Caprylyl Glycol, Hydroxyacetophenone, Polyacrylate Crosspolymer-6, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Xanthan Gum, Dimethicone, Carbomer, Ethylhexylglycerin, Potassium Sorbate, Phenoxyethanol, Parfum/Fragrance, Leuconostoc/Radish Root Ferment Filtrate, Citral, Limonene, Linalool

The activation of ICD relies on the combined action of ER stress and ROS generation and requires the production of sufficient DAMPs in the TME [49]