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Some peptides act directly on endocrine glands

Mechanistically, the bacterium activates microglia via the Toll-like receptor 4 (TLR4) signaling pathway, promoting the release of inflammatory factors (e.g., TNF-) and the formation of secretory vesicles that damage cerebral microvascular endothelial cells and ultimately disrupt the BBB [143,144,145,146]

Ferroptosis is a type of regulated cell death characterized by the accumulation of intracellular iron and lipid ROS

3 A pulmonary embolism is generally marked by symptoms such as sharp chest pain with breathing, shortness of breath, fatigue, back pain, and fainting

Mreaux, J.-L