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After treatment with ALA, the increase in the FMD and the decrease in superoxide anion were significant

(Verlag von Gustav Fischer, 1878)

The toxicity of nanoparticles is related to various factors such as route of administration, ingested dose, surface modification, particle size, shape, polydispersity coefficient, and others (Teleanu et al., 2018

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The advancement of kidney-targeted drug delivery systems utilizing low-molecular-weight proteins and chitosan is a promising strategy for targeting proximal tubular and mesangial cells, which are ideal for particulate drug delivery systems such as nanoparticles or liposomes [75]