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Ethical Approval This is a systematic review, therefore an ethical approval was not required

At 25M of menadione, there was a 13.3-fold increase for HEK-293 cells and 11.5-fold increase for K-562 cells in the amount of oxidized glutathione compared to the control

Commonly measured antioxidant enzymes include glutathione (GSH), total antioxidant capacity (TAC), glutathione peroxidase (GPx), and superoxide dismutase (SOD), while malondialdehyde (MDA) is often used as a marker of oxidative stress