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It has been used extensively in animal studies, human cell models, and increasingly in off-label therapeutic settings, with minimal toxicity or organ stress reported

Patients with biopsy-confirmed regression in fibrosis stage (between baseline and EOT) had a statistically significant drop in MASH-fibrosis score (average drop of 8%

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4 Another important component of the extracellular matrix is hyaluronic acid, which contributes to water retention in tissues and to their structural integrity

This can lead to an increased risk of heart failure or irregular heart rhythms