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[DOI] [PMC free article] [PubMed] [Google Scholar] 248.Sies H

3.6.2 Ferroptosis dysregulation drives RCC drug resistance Sorafenib, the first Food and Drug Administration (FDA)-approved multi-kinase inhibitor for metastatic ccRCC (253), was initially shown to induce ferroptosis by inhibiting SLC7A11 (254)

Even in states of severe intrauterine hemolysis from conditions such as Rh or other isoimmunizations, the degree of anemia by far exceeds the level of hyperbilirubinemia, and clinical jaundice is usually mild at birth