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For in vivo experiments, U87MG tumor-bearing mice were intraperitoneally administered pro-GA (25 mg/kg) or IKE (25 mg/kg) three times per week for three weeks for tissue distribution analysis

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And more meaningfully, it remains an open question how to promote the effect of emerging immunotherapy, represented by PD-1/PD-L1 blockade, by manipulating ferroptosis, and how to strike a balance between the anti-tumor and pro-tumor effects of ferroptosis

For information on how researchers administer BPC-157 , including routes of administration and timing protocols, several resources provide detailed guidance

6f), but increase the percentage of Arg-1 positive macrophages (Fig