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In db/db mouse kidney tissue, SNHG1, ACSL4, and miR-16-5p expression levels are abnormal but can be normalized by Fer-1 treatment or SNHG1 knockdown in both db/db mice and high glucose-treated HK-2 cells [133]

In the context of neurodegenerative diseases, GPS has shown neuroprotective capabilities, shielding neurons from damage (Zhang L

Biochemistry 30: 613619 [DOI] [PubMed] [Google Scholar] Molteni SN, Fassio A, Ciriolo MR, Filomeni G, Pasqualetto E, Fagioli C, Sitia R (2004) Glutathione limits Ero1-dependent oxidation in the endoplasmic reticulum

It reflects the number of harmful particles, not just the amount of cholesterol

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