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More studies are warranted to explore the impact of 4-HNE on cartilage homeostasis and the therapeutic potential by scavenging 4-HNE in OA

Numerous preclinical reports have highlighted the ability of curcumin to restore reduced GSH levels and the activities of GSH-related antioxidant enzymes in the myocardium after exposure to cardiotoxic factors, for example, DOX, I/R, diabetes, hyperthyroid conditions, and copper sulfate [184,185,186,187,188]

Those who follow a vegetarian or vegan diet may be at risk for B12 deficiency, as this vitamin is primarily found in animal products

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