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Future research endeavors should aim to delineate PAs precise molecular targets within these broader networks, possibly utilizing unbiased approaches like affinity-based proteomics or genome-wide CRISPR/Cas9 screens to identify direct interactors and further elucidate PAs mechanism of action

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There remains a need to identify therapeutic agents that may be useful in the treatment of PTLDS and/or therapeutic agents that may be useful in the treatment of the early phase of the disease thereby preventing the onset of PTLDS

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