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Description

Protein degradation by the ubiquitin-proteasome pathway in normal and disease states

Genetic screen-based identification of gene regulators of GBM One cell type (OCT) Perturb-Seq OCT targeted screens are defined as genetic screens performed in a single cell line with a focused gene library, as opposed to being genome wide [37, 38]

Despite repeated reports of selective cancer cell toxicity induced by high-dose vitamin C treatment in vitro and in mouse models, the mechanism of action has remained elusive