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doi: 10.1016/0039-6257(83)90140-6

When to see a dermatologist Some situations require professional help: Immediate dermatologist visit needed: Severe allergic reaction: Hives, extensive rash Swelling of face, lips, or throat Difficulty breathing Severe, spreading redness This is medical emergency

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Each of these nucleosomes has two subunits, each comprising the core histones H2A, H2B, H3 and H4, and a linker histone called H1 that acts as stabilizer

4.2 Autoimmune diseases Autoimmune diseases (AIDs) are a group of disorders in which the immune system develops an immune response to its own normal tissue components (189), characterized by chronic, systemic, and excessive immune activation and inflammation, ultimately leading to organ destruction or dysfunction (190)