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Interestingly, FTC patients with partially or hypermethylated SLC5A8 exhibited higher recurrence rates during a 5-year follow-up compared to those with hypomethylated SLC5A8 , suggesting that methylation analysis of this gene could serve as a valuable prognostic tool for predicting clinical outcomes in FTC patients [210]

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The Nrf2-keap1 system halts this inflammatory axis by finding redox imbalance through electrophilic or oxidative changes to Keap1 cysteines