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Vitamin B12 is an essential compound we get from animal based food sources

doi: 10.3389/fimmu.2019.02090 4 de OliveiraFAGuimaresJVdos ReisMATeixeiraVdePA

CDX2 is also inhibited by SMYD2 -mediated MEX3A to enhance CRC progression (Pan et al., 2022), Decreased expression of CDX2 is more dependent on the CpG island hypermethylation phenotype (CIMP-H) (Lee et al., 2022)