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Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7

The metabolism of alcohol generates potentially dangerous by-products like acetaldehyde and free radicals, which contribute significantly to alcohol-induced liver damage

Van Der Vliet A, Nguyen MN, Shigenaga MK, Eiserich JP, Marelich GP, Cross CE: Myeloperoxidase and protein oxidation in cystic fibrosis

GPS, however, seems to regulate HSC activation in a manner that encourages the secretion of growth factors and cytokines conducive to liver healing, thereby preventing excessive fibrosis