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Replying to @Angela Vitamin B12 supplements can trigger an acne like eruption, as can vitamin B6 & biotin supplements. In contrast to acne, there are no comedones. Once the supplements are stopped, Vitamin B12 induced acneiform eruption PMC Do Vitamin B12 Supplements Cause Acne? Facial Acne after B12 Loading Dose Pernicious Anaemi Can B12 and Biotin Cause Acne? Emilia Nutrition
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