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In such cases, someone with the MTHFR gene variation may seem to have elevated levels of B12 (as well as elevated levels of homocysteine), but will actually have low levels of B12 in the form that their body can utilize

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But I think thats missing the forest for the trees

The following press release from #STOPTHEBOP gives background on this important issue: On July 31, the California Board of Pharmacy (BOP) was met with overwhelming opposition to their proposed regulations that would severely restrict the production and administration of essential treatments such as glutathione, NAD, and methylcobalamin, the active form of vitamin B12

Most patients keep the same weekly dose they tolerated previously, with B12 added