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Cyprotex offers the Ames test as an early stage assessment of genotoxicity using a miniaturised screening version which requires less compound and evaluates two of the most common mutations, TA98 and TA100

Metformin, compound C (dorsomorphin), and erastin were purchased from Selleck Chemicals, Yuanye Biotechnology, and MedChemExpress, respectively

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Active components from Dendrobium huoshanense have been demonstrated to improve lipid metabolism and intestinal barrier function by modulating GM structure, thereby mitigating liver injury [14]

A history of other substance use, higher socioeconomic status, or exposure to family violence or substance abuse has also been reported more often in this population (37, 38)