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Mullur et al, 2014

Genetic variation and gene expression in antioxidant related enzymes and risk of COPD: a systematic review

In the FLS of RA patients, the expression of anti-apoptotic mediators such as Bcl-2, Bcl-xL, Mcl-2 and FLICE inhibitory protein (FLIP) is upregulated, whereas the expression of pro-apoptotic proteins such as TRAIL, p53 up-regulator of apoptosis (PUMA) and BAX is downregulated

Aging Cell 18(6):e13031 Jin T, Zhang Y, Botchway BOA, Zhang J, Fan R, Zhang Y, Liu X (2022) Curcumin can improve Parkinsons disease via activating BDNF/PI3k/Akt signaling pathways

A striking example involves the Y-satellite RNA of CMV: Its derived siRNA targets the chlorophyll biosynthesis gene CHLI in tobacco, inducing leaf yellowing to reduce photosynthetic efficiency and conserve energy