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This study aims to test the hypothesis that the antioxidant effect of the synthetic tetrapeptide AEDG (Ala-Glu-Asp-Gly, Epitalon) improves the delayed healing process associated with hyperglycemia in DR, using a high glucose (HG)-injured human retinal pigment epithelial cell line (ARPE-19)

Normal B12 ranges typically fall between 200-900 pg/mL, though functional B12 status is better assessed by methylmalonic acid (MMA) and homocysteine levels

Assess peptide stability and degradation kinetics under controlled experimental conditions

Long-Term Storage: Store at -20C (Freezer) to maintain maximum stability of the HGF mimetics and SNDRI components

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