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At the mRNA level, we observed irregular expression patterns of PI3K, AKT, and mTOR genes across biological samples

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Adjusting the GSSG/GSH ratio affects ROS levels ( FIGURE 3 GPX4 and Ferroptosis GPX4 is a protein that protects cell membranes against lipid peroxidation and converts GSH to GSSG

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It was also noted that the GSK-3 down-regulation effect was improved approximately 5056% when additional applying with FUS-BBB opening efficiency after GSK-3 inhibitor administration (0.48 0.03% vs