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However, excessive levels of copper in the body can lead to a condition called copper overload, which can have severe consequences

Clioquinol promotes cancer cell toxicity through tumor necrosis factor alpha release from macrophages

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Glutarate, a product of lysine or tryptophan catabolism, is a particularly interesting metabolite, as it can be conjugated to proteins or nonprotein substrates (for example, fatty acids), with diverse outcomes for mitochondrial function 5,6,7 , metabolism 8 and T cell immunity 9

Future research should focus on larger, well-designed clinical trials to clarify efficacy, dose-response relationships, and long-term safety