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We propose patients who pause treatment may have testing repeated after 2 weeks, while those with resolving aminotransferase elevations may reinitiate omaveloxolone with stepwise dose titrations and testing every 2 weeks for 3 months

Fan YL, Sun QM, Li X, Feng JT, Ao Z, Li X et al

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2.2 Major physiological changes to account for the disease pathology of -synuclein Misfolding of -synuclein has been linked to a plethora of cognitive ailments arising from the death of dopaminergic neurons and collectively referred to as synucleinopathies

Tyrosinase is an enzyme that catalyzes the biosynthesis of melanin which is the culprit for skin darkening