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[6] Evidence There is little direct evidence to support the popular methylation protocols

Bisphosphonates (alendronate, risedronate): Used for osteoporosis, these medications are known to cause esophageal irritation and must be taken upright with a full glass of water

Methylcobalamin, the natural B12 form that your body actually prefers because it doesnt have to detoxify the cyano part, is simply more expensive to manufacture

Vitamin B12 is also known as Cobalamin, that an individual needs to consume to maintain health

Stroke and Excitotoxicity Protection Excitotoxicity protection appeared in stroke models where bilateral carotid artery clamping produces ischemia-reperfusion injury with massive glutamate release