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The harmful impacts of radiation on cells are mainly exerted by free radicals like hydroxyl, superoxide, and hydrogen peroxide (57), which can damage lipids, nucleic acids, and proteins, leading to cellular dysfunction and even apoptosis (5860)

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For the L-carnitine challenge study ( n = 47), male and female homozygous APOE2-, APOE3-, and APOE4-TR mice were euthanized at 53-weeks (Supplementary Table S3)

Thus, we deduced that dietary L-carnitine supplementation can stimulate the expression of mTOR in fish by increasing the leucine concentration in the feeding state

Table 1 gives an overview of the study participants