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bed rest is no longer routinely recommended per ASH guidelines Special Populations Pregnancy: LMWH (enoxaparin, dalteparin) throughout pregnancy

Finally, calciumcalmodulin complexes activate NOS, which facilitates NOS-dependent NO production (Tang et al., 2014)

After a period of extended freedom from attacks, a carefully supervised tapered discontinuation may be attempted, but there is evidence that this may often be difficult to accomplish without recurrence of symptoms and/or the manifestation of withdrawal phenomena

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