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The increased expression of IL-1b and IL-6 after prolonged treatment with HNG or SHLP3 could indicate that the peptides induced intrinsic effects independent of gentamicin by binding to surface receptors such as the cytokine receptor complex, FPRL receptors, or as yet unknown receptors [17, 18]

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(2) Studies have suggested that Thymalin, a naturally occurring polypeptide, is primarily found in the young epidermal cells of the thymus gland