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In the UC model mice, it has been reported that the length of the large intestine is reduced due to inflammation

& Ziegler, D

Whereas the deficiency and overload of iron are the result of defective metabolism and are associated with several diseases [9]

The NLRP3 inflammasomes are central to the initiation of inflammatory responses by activating caspase-1 and promoting the release of pro-inflammatory cytokines, particularly interleukin (IL)-1 and IL-18