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Zhang R, Wang C, Zheng X, Li S, Zhang W, Kang Z, et al

Bioinformatics and statistics With the rapid development of omics technologies, novel biomarker discovery in disease or toxicity is now mostly concerned with comprehensive analysis of potential biomarkers in biological samples such as cells, tissues or biofluids in a discovery-based or hypothesis-generating approach rather than the traditional hypothesis-based approach

Enhanced lipid peroxidation upon GPX4 deletion (GPX4 Mye/ ) was shown to increase the expression of caspase 11 and N-GSDMD in response to LPS transfection and E-coli infection [12]