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Clin Immunol 159:122127

Szczuko, M., Syrenicz, A., Szymkowiak, K., Przybylska, A., Szczuko, U., Pobocki, J., & Kulpa, D

ROC analysis based on pathway scores revealed that pathways such as alanine, aspartate, and glutamate metabolism, inositol phosphate metabolism, and mitochondrial beta-oxidation of unsaturated fatty acids exhibited an AUC greater than 0.8 in the PBMC data (Table S16)

Thus, benfotiamine was shown to be effective in suppressing both inflammation and oxidative stress, two hallmarks of chronically activated microglia [19]