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If iron ions serve as key mediators, strategies should target ferroportin and iron transport

showed that DEX increased the expression levels of SLC7A11 and GPX4 and protected H9C2 cells from hypoxia/reoxygenation injury through the AMPK/GSK-3/Nrf2 axis [233]

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Remember, seeking treatment early is essential

The pruritus of cholestasis: From bile acids to opiate agonists: Relevant after all these years