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While ALT is present only in cytoplasm, AST is present in both cytoplasm and mitochondria

doi: 10.1016/j.neurobiolaging.2020.11.015

Epoxyketooctadecenoic acid (EKODE) was markedly increased in the azoxymethane (AOM)/dextran sodium sulfate (DSS)-induced CRC mouse model, activating the NF-B and JNK pathways in macrophages (Lei et al