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As the title of the study states, cyanocobalaminthe most common form of supplemental B12may be beneficial in the treatment of recurrent aphthous ulcers [canker sores] even when vitamin B12 levels are normal. The researchers took a group of 72 patients with frequent canker sores and gave them vitamin B12, regardless of what their levels were

W., Elgersma, Y., Singh, N., Wanders, R

However, any severe or prolonged symptoms should be evaluated

6, over the course of the accelerated heat stress study, the characteristic SH and COO- peaks decrease as a function of the applied heat stress