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Previously, we found that rotenone could negatively regulate mTOR-mediated p70S6K and 4E-BP1/Eif4E pathways, that leads to caspase-3 dependent neuronal apoptosis in vitro 15

It is desirable to obtain backbone reagent carrying 32 amino groups, consequently seven lysines would be attached to each arm of a 4-arm PEG, or five lysines would be attached to each arm of a 8-arm PEG