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The procedure achieved an increase in central corneal thickness of 285 99 m in the Iranian and 209 18 m in the Indian cohort at 2 years post-operative, also flattening the excessively steep cornea with a mean decrease in K max of 11.2 8.9 D in the Iranian and 13.9 7.9 D in the Indian cohort, meeting efficacy criteria in 90% (18/20) of cases, while vision gain was achieved in 95% (19/20) of cases at 24 months

Phototoxicity is generally dose-dependent and may occur upon first exposure to the medication without the need for prior sensitisation (Mehrholz 2020)

S3D and Fig

Betulinic acid alleviates endoplasmic reticulum stress-mediated nonalcoholic fatty liver disease through activation of farnesoid X receptors in mice