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It inhibits the NF-kappaB signaling pathway (a master regulator of inflammatory gene expression inside cells) and the MAPK pathway (another inflammatory signaling cascade), reducing the production of cytokines that damage follicle cells and disrupt normal hair cycling under conditions of chronic scalp inflammation [1]

Compared with the single components, the stack trades per-compound dose flexibility for convenience

Okamura T, Tsujitani S, Korenaga D, Haraguchi M, Baba H, Hiramoto Y, Sugimachi K

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No calcitonin change in a person taking dulaglutide diagnosed with pre-existing medullary thyroid cancer