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The intestinal epithelium is the location where enzymes such as diamine oxidase and lactase are synthesised, which is why morphological changes to the intestinal mucosa caused by inflammation also lead to reduced synthesis of these essential enzymes

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Results: Berberine reduced renal injury in STZ-induced DN rat model, as evidenced by the decrease in fasting blood glucose, ratio of kidney weight to body weight, 24-h urinary protein, serum creatinine, and blood urine nitrogen

In a 15 ml centrifuge tube carefully layer 6 ml of diluted blood over 3 ml of the density barrier (avoid mixing at the interface)