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It downregulated ACSL4 and CD71 expression, significantly increased the expression of System Xc , GPX4, and Ferritin, reduced ROS levels, and inhibited ferroptosis, inflammatory responses, and mitochondrial dysfunction in BV2 cells

RAGE, a member of the immunoglobulin superfamily, is highly expressed on the surface of various cell types, with particularly high expression in lung tissue, and can bind to multiple ligands (Su et al., 2009)

The team also studied for the first time the anticancer properties of the sterol 10-epicatechin methyl ether

Kern, P

When cells are engineered to overproduce Hsp70.1, the cells show higher ASM activity than did their normal counterparts, and are protected against stress-induced lysosomal damage